Role of main RNA modifications in cancer: N6-methyladenosine, 5-methylcytosine, and pseudouridine

Abstract Cancer is one of the major diseases threatening human life and health worldwide. Epigenetic modification refers to heritable changes in the genetic material without any changes in the nucleic acid sequence and results in heritable phenotypic changes. Epigenetic modifications regulate many b...

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Bibliographic Details
Main Authors: Chen Xue, Qingfei Chu, Qiuxian Zheng, Shiman Jiang, Zhengyi Bao, Yuanshuai Su, Juan Lu, Lanjuan Li
Format: Article
Language:English
Published: Nature Publishing Group 2022-04-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-022-01003-0