Effect of Acrylamide on Oocyte Nuclear Maturation and Cumulus Cells Apoptosis in Mouse In Vitro.

Acrylamide (ACR) is a chemical compound with severe neurotoxicity, genotoxicity, carcinogenicity and reproductive toxicity. Recent studies showed that ACR impairs the function of reproductive organs, e.g., epididymis and testes. In vitro maturation of mouse oocyte is a sensitive assay to identify po...

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Bibliographic Details
Main Authors: Shuzhen Liu, Ligang Jiang, Tao Zhong, Shuhui Kong, Rongbin Zheng, Fengyun Kong, Cong Zhang, Lei Zhang, Liguo An
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4537141?pdf=render