Long-read sequencing reveals complex patterns of wraparound transcription in polyomaviruses.

Polyomaviruses (PyV) are ubiquitous pathogens that can cause devastating human diseases. Due to the small size of their genomes, PyV utilize complex patterns of RNA splicing to maximize their coding capacity. Despite the importance of PyV to human disease, their transcriptome architecture is poorly...

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Bibliographic Details
Main Authors: Jason Nomburg, Wei Zou, Thomas C Frost, Chandreyee Datta, Shobha Vasudevan, Gabriel J Starrett, Michael J Imperiale, Matthew Meyerson, James A DeCaprio
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-04-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1010401