Cardiovascular Profile of Xanthone-Based 1,4 Dihydropyridines Bearing a Lidoflazine Pharmacophore Fragment

Cardiovascular Profile of Xanthone-Based 1,4 Dihydropyridines Bearing a Lidoflazine Pharmacophore Fragment

As a follow-up to our previous studies on differently substituted 1,4-dihydropyridines endowed with a peculiar cardiac selectivity, in this paper, a small series of hybrid compounds bearing the pharmacophore fragment of lidoflazine in position 2 or 3 on a 4-(xanthen-9-one)-dihydropyridine core was r...

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Bibliographic Details
Main Authors: Alessandra Bisi, Matteo Micucci, Silvia Gobbi, Federica Belluti, Roberta Budriesi, Angela Rampa
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:Molecules
Subjects:
xanthone
1,4-dihydropyridine
lidoflazine
calcium channels
hybrid compounds
Online Access:https://www.mdpi.com/1420-3049/23/12/3088

Internet

https://www.mdpi.com/1420-3049/23/12/3088

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