Application of Phosphine-Phosphite Ligands in the Iridium Catalyzed Enantioselective Hydrogenation of 2-Methylquinoline

The hydrogenation of 2-methylquinoline with Ir catalysts based on chiral phosphine-phosphites has been investigated. It has been observed that the reaction is very sensitive to the nature of the ligand. Optimization of the catalyst, allowed by the highly modular structure of these phosphine-phosphit...

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Bibliographic Details
Main Authors: Miguel Rubio, Antonio Pizzano
Format: Article
Language:English
Published: MDPI AG 2010-10-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/15/11/7732/