A biomaterial with a channel-like pore architecture induces endochondral healing of bone defects
A bioengineering approach to enhance the regeneration of large bone defects is lacking. Here, the authors show that a biomaterial scaffold with a channel-like pore architecture enables organized endochondral ossification through directional cell recruitment and extracellular matrix alignment.
Hlavní autoři: | , , , , , , , , , , , , |
---|---|
Médium: | Článek |
Jazyk: | English |
Vydáno: |
Nature Portfolio
2018-10-01
|
Edice: | Nature Communications |
On-line přístup: | https://doi.org/10.1038/s41467-018-06504-7 |