Knowledge graph analytics platform with LINCS and IDG for Parkinson's disease target illumination

Knowledge graph analytics platform with LINCS and IDG for Parkinson's disease target illumination

Abstract Background LINCS, "Library of Integrated Network-based Cellular Signatures", and IDG, "Illuminating the Druggable Genome", are both NIH projects and consortia that have generated rich datasets for the study of the molecular basis of human health and disease. LINCS L1000...

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Bibliographic Details
Main Authors: Jeremy J. Yang, Christopher R. Gessner, Joel L. Duerksen, Daniel Biber, Jessica L. Binder, Murat Ozturk, Brian Foote, Robin McEntire, Kyle Stirling, Ying Ding, David J. Wild
Format: Article
Language:English
Published: BMC 2022-01-01
Series:BMC Bioinformatics
Subjects:
Knowledge graph
Graph analytics
Systems biology
Drug discovery
Drug target
Druggable genome
Online Access:https://doi.org/10.1186/s12859-021-04530-9

Internet

https://doi.org/10.1186/s12859-021-04530-9

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