An RNA Interference (RNAi) Toolkit and Its Utility for Functional Genetic Analysis of <i>Leishmania</i> (<i>Viannia</i>)

RNA interference (RNAi) is a powerful tool whose efficacy against a broad range of targets enables functional genetic tests individually or systematically. However, the RNAi pathway has been lost in evolution by a variety of eukaryotes including most Leishmania sp. RNAi was retained in species of th...

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Bibliographic Details
Main Authors: Lon-Fye Lye, Katherine L. Owens, Soojin Jang, Joseph E. Marcus, Erin A. Brettmann, Stephen M. Beverley
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/14/1/93