Polymer-Stabilized Elemental Boron Nanoparticles for Boron Neutron Capture Therapy: Initial Irradiation Experiments

Polymer-Stabilized Elemental Boron Nanoparticles for Boron Neutron Capture Therapy: Initial Irradiation Experiments

Sufficient boron-10 isotope (<sup>10</sup>B) accumulation by tumor cells is one of the main requirements for successful boron neutron capture therapy (BNCT). The inability of the clinically registered <sup>10</sup>B-containing borophenylalanine (BPA) to maintain a high boron...

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Bibliographic Details
Main Authors: Alexander Zaboronok, Polina Khaptakhanova, Sergey Uspenskii, Raman Bekarevich, Ludmila Mechetina, Olga Volkova, Bryan J. Mathis, Vladimir Kanygin, Eiichi Ishikawa, Anna Kasatova, Dmitrii Kasatov, Ivan Shchudlo, Tatiana Sycheva, Sergey Taskaev, Akira Matsumura
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Pharmaceutics
Subjects:
elemental boron nanoparticles
hydroxyethylcellulose
polymer stabilization
boron neutron capture therapy
accelerator-based neutron source
Online Access:https://www.mdpi.com/1999-4923/14/4/761

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https://www.mdpi.com/1999-4923/14/4/761

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