Macaque-tropic human immunodeficiency virus type 1 (HIV-1mt): Breaking out of the host restriction factors

Macaque monkeys serve as important animal models for understanding the pathogenesis of lentiviral infections. Since human immunodeficiency virus type 1 (HIV-1) hardly replicates in macaque cells, simian immunodeficiency virus (SIV) or chimeric viruses between HIV-1 and SIV (SHIV) have been used as c...

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Bibliographic Details
Main Authors: Akatsuki eSaito, Hirofumi eAkari
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-07-01
Series:Frontiers in Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2013.00187/full