Longitudinal whole blood transcriptomic analysis characterizes neutrophil activation and interferon signaling in moderate and severe COVID-19

Longitudinal whole blood transcriptomic analysis characterizes neutrophil activation and interferon signaling in moderate and severe COVID-19

Abstract A maladaptive inflammatory response has been implicated in the pathogenesis of severe COVID-19. This study aimed to characterize the temporal dynamics of this response and investigate whether severe disease is associated with distinct gene expression patterns. We performed microarray analys...

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Bibliographic Details
Main Authors: Christian Prebensen, Yohan Lefol, Peder L. Myhre, Torben Lüders, Christine Jonassen, Anita Blomfeldt, Torbjørn Omland, Hilde Nilsen, Jan-Erik Berdal
Format: Article
Language:English
Published: Nature Portfolio 2023-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-37606-y

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https://doi.org/10.1038/s41598-023-37606-y

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