Daily oscillation of the excitation/inhibition ratio is disrupted in two mouse models of autism

Daily oscillation of the excitation/inhibition ratio is disrupted in two mouse models of autism

Show other versions (1)

Summary: Alterations to the excitation/inhibition (E/I) ratio are postulated to underlie behavioral phenotypes in autism spectrum disorder (ASD) patients and mouse models. However, in wild type mice the E/I ratio is not constant, but instead oscillates across the 24-h day. Therefore, we tested wheth...

Full description

Bibliographic Details
Main Authors: Michelle C.D. Bridi, Nancy Luo, Grace Kim, Benjamin J. Menarchek, Rachel A. Lee, Bryan Rodriguez, Daniel Severin, Christian Wesselborg, Caroline O’Ferrall, Ruchit Patel, Sarah Bertrand, Sujatha Kannan, Alfredo Kirkwood, Cristian Moreno, Altagracia Contreras
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:iScience
Subjects:
Neuroscience
Sensory neuroscience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224027214

Internet

http://www.sciencedirect.com/science/article/pii/S2589004224027214

Similar Items