The HILDA complex coordinates a conditional switch in the 3'-untranslated region of the VEGFA mRNA.
Cell regulatory circuits integrate diverse, and sometimes conflicting, environmental cues to generate appropriate, condition-dependent responses. Here, we elucidate the components and mechanisms driving a protein-directed RNA switch in the 3'UTR of vascular endothelial growth factor (VEGF)-A. W...
Principais autores: | , , , , , , |
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Formato: | Artigo |
Idioma: | English |
Publicado em: |
Public Library of Science (PLoS)
2013-01-01
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coleção: | PLoS Biology |
Acesso em linha: | https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.1001635&type=printable |