The HILDA complex coordinates a conditional switch in the 3'-untranslated region of the VEGFA mRNA.

Cell regulatory circuits integrate diverse, and sometimes conflicting, environmental cues to generate appropriate, condition-dependent responses. Here, we elucidate the components and mechanisms driving a protein-directed RNA switch in the 3'UTR of vascular endothelial growth factor (VEGF)-A. W...

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Detalhes bibliográficos
Principais autores: Peng Yao, Alka A Potdar, Partho Sarothi Ray, Sandeepa M Eswarappa, Andrew C Flagg, Belinda Willard, Paul L Fox
Formato: Artigo
Idioma:English
Publicado em: Public Library of Science (PLoS) 2013-01-01
coleção:PLoS Biology
Acesso em linha:https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.1001635&type=printable