Differentiation of Memory CD8 T Cells Unravel Gene Expression Pattern Common to Effector and Memory Precursors

Differentiation of Memory CD8 T Cells Unravel Gene Expression Pattern Common to Effector and Memory Precursors

Long-term immunological protection relies on the differentiation and maintenance of memory lymphocytes. Since the knowledge of memory generation has been centered on in vivo models of infection, there are obstacles to deep molecular analysis of differentiating subsets. Here we defined a novel in vit...

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Bibliographic Details
Main Authors: Vanessa Neitzke-Montinelli, Carolina Calôba, Guilherme Melo, Bianca B. Frade, Enzo Caramez, Luciano Mazzoccoli, André N. A. Gonçalves, Helder I. Nakaya, Renata M. Pereira, Miriam B. F. Werneck, João P. B. Viola
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Immunology
Subjects:
CD8 T cell differentiation
immunological memory
cytotoxicity
adoptive cell transfer
immunotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.840203/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.840203/full

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