Assessment of Micafungin Dosage Regimens in Patients with Cancer Using Pharmacokinetic/Pharmacodynamic Modeling and Monte Carlo Simulation

Assessment of Micafungin Dosage Regimens in Patients with Cancer Using Pharmacokinetic/Pharmacodynamic Modeling and Monte Carlo Simulation

Micafungin is widely used for invasive candidiasis, especially in critically ill patients and those with cancer, and for empirical antifungal therapy in patients with neutropenic fever. This is the first study to investigate the pharmacokinetics and disposition parameters of micafungin in patients w...

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Bibliographic Details
Main Authors: Saeed Alqahtani, Asma Alfarhan, Abdullah Alsultan, Emad Alsarhani, Abdulaziz Alsubaie, Yousif Asiri
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Antibiotics
Subjects:
micafungin
cancer
population pharmacokinetics
modeling
Monte Carlo simulation
Online Access:https://www.mdpi.com/2079-6382/10/11/1363

Internet

https://www.mdpi.com/2079-6382/10/11/1363

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