TGF-β contamination of purified recombinant GDF15.

Purified recombinant proteins for use in biomedical research are invaluable to investigate protein function. However, purity varies in protein batches made in mammalian expression systems, such as CHO-cells or HEK293-cells. This study points to caution while investigating effects of proteins related...

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Bibliographic Details
Main Authors: Oddrun Elise Olsen, Anette Skjærvik, Berit Fladvad Størdal, Anders Sundan, Toril Holien
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5697882?pdf=render