Attenuates of NAD+ impair BMSC osteogenesis and fracture repair through OXPHOS

Attenuates of NAD+ impair BMSC osteogenesis and fracture repair through OXPHOS

Abstract Background Controlling the adipo-osteogenic lineage commitment of bone marrow mesenchymal stem cell (BMSC) in favor of osteogenesis is considered a promising approach for bone regeneration and repair. Accumulating evidence indicates that oxidative phosphorylation (OXPHOS) is involved in reg...

Full description

Bibliographic Details
Main Authors: Boer Li, Yu Shi, Mengyu Liu, Fanzi Wu, Xuchen Hu, Fanyuan Yu, Chenglin Wang, Ling Ye
Format: Article
Language:English
Published: BMC 2022-02-01
Series:Stem Cell Research & Therapy
Subjects:
BMSC
Differentiation
NAD
OXPHOS
Energy metabolism
Online Access:https://doi.org/10.1186/s13287-022-02748-9

Internet

https://doi.org/10.1186/s13287-022-02748-9

Similar Items