NEK2 promotes esophageal squamous cell carcinoma cell proliferation, migration and invasion through the Wnt/β-catenin signaling pathway

NEK2 promotes esophageal squamous cell carcinoma cell proliferation, migration and invasion through the Wnt/β-catenin signaling pathway

Abstract Objectives The NEK2 (never in mitosis gene A-related kinase 2), a serine/threonine kinase involved in chromosome instability and tumorigenesis. Hence, this study aimed to explore the molecular function of NEK2 in esophageal squamous cell carcinoma (ESCC). Methods By available transcriptome...

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Bibliographic Details
Main Authors: Dong Guo, Weinan Yao, Xingyu Du, Jing Dong, Xueyuan Zhang, Wenbin Shen, Shuchai Zhu
Format: Article
Language:English
Published: Springer 2023-05-01
Series:Discover Oncology
Subjects:
NEK2
Invasion
Wnt/β-catenin
Esophageal squamous cell carcinoma
Proliferation
Online Access:https://doi.org/10.1007/s12672-023-00692-5

Internet

https://doi.org/10.1007/s12672-023-00692-5

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