scMEB: a fast and clustering-independent method for detecting differentially expressed genes in single-cell RNA-seq data

Abstract Background Cell clustering is a prerequisite for identifying differentially expressed genes (DEGs) in single-cell RNA sequencing (scRNA-seq) data. Obtaining a perfect clustering result is of central importance for subsequent analyses, but not easy. Additionally, the increase in cell through...

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Bibliographic Details
Main Authors: Jiadi Zhu, Youlong Yang
Format: Article
Language:English
Published: BMC 2023-05-01
Series:BMC Genomics
Subjects:
Online Access:https://doi.org/10.1186/s12864-023-09374-6