Employing hypoxia characterization to predict tumour immune microenvironment, treatment sensitivity and prognosis in hepatocellular carcinoma

Employing hypoxia characterization to predict tumour immune microenvironment, treatment sensitivity and prognosis in hepatocellular carcinoma

The hypoxic microenvironment was recognized as a major driving force of the malignant phenotype in hepatocellular carcinoma (HCC), which contributes to tumour immune microenvironment (TIM) remodeling and tumor progression. Dysregulated hypoxia-related genes (HRGs) result in treatment resistance and...

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Bibliographic Details
Main Authors: Fanhong Zeng, Yue Zhang, Xu Han, Min Zeng, Yi Gao, Jun Weng
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Hepatocellular carcinoma
Hypoxia
Gene set enrichment analysis
Tumor immune microenvironment
Risk model
Treatment sensitivity
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037021001057

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http://www.sciencedirect.com/science/article/pii/S2001037021001057

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