Macrophage colony-stimulating factor ameliorates myocardial injury in mice after myocardial infarction by regulating cardiac macrophages through the P2X7R/NLRP3/IL-1β signal pathway

Macrophage colony-stimulating factor ameliorates myocardial injury in mice after myocardial infarction by regulating cardiac macrophages through the P2X7R/NLRP3/IL-1β signal pathway

Aims: To investigate the effects of M-CSF on myocardial injury in mice after MI by regulating different types of cardiac macrophages through the P2X7R/NLRP3/IL-1β signal pathway. Methods: A total of 60 C57BL/6J WT mice were used, with the Sham Group subjected to ligation without ligation through the...

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Bibliographic Details
Main Authors: Shu-Juan Zhang, Cong-Xin Huang, Qing-Yan Zhao, He Huang, Jian Zhang
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Heliyon
Subjects:
Myocardial infarction
Macrophage
Inflammation
Apoptosis
Myocardial injury
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023080131

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http://www.sciencedirect.com/science/article/pii/S2405844023080131

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