Transcriptome variations among human embryonic stem cell lines are associated with their differentiation propensity.

Human embryonic stem cells (hESCs) have the potential to form any cell type in the body, making them attractive cell sources in drug screening, regenerative medicine, disease and developmental processes modeling. However, not all hESC lines have the equal potency to generate desired cell types in vi...

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Bibliographic Details
Main Authors: Changbin Sun, Jiawen Zhang, Dongmin Zheng, Jian Wang, Huanming Yang, Xi Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0192625