Assessment of HER2/Neu status by fluorescence in situ hybridization in immunohistochemistry-equivocal cases of invasive ductal carcinoma and aberrant signal patterns: A study at a tertiary cancer center

Assessment of HER2/Neu status by fluorescence in situ hybridization in immunohistochemistry-equivocal cases of invasive ductal carcinoma and aberrant signal patterns: A study at a tertiary cancer center

Introduction: HER-2/neu status determines the eligibility for targeted therapy with trastuzumab in breast carcinoma. Evaluation for HER-2/neu protein expression by immunohistochemistry (IHC) and gene amplification by fluorescence in situ hybridization (FISH) has become the gold standard. Aims: Since...

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Bibliographic Details
Main Authors: Sudha S Murthy, D G Sandhya, Faiq Ahmed, K Iravathy Goud, Monal Dayal, K Suseela, Senthil J Rajappa
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2011-01-01
Series:Indian Journal of Pathology and Microbiology
Subjects:
Breast cancer
FISH
HER-2/neu
invasive ductal carcinomas
unusual signal patterns
Online Access:http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2011;volume=54;issue=3;spage=532;epage=538;aulast=Murthy

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http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2011;volume=54;issue=3;spage=532;epage=538;aulast=Murthy

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