CTB-targeted protocells enhance ability of lanthionine ketenamine analogs to induce autophagy in motor neuron-like cells

CTB-targeted protocells enhance ability of lanthionine ketenamine analogs to induce autophagy in motor neuron-like cells

Abstract Impaired autophagy, a cellular digestion process that eliminates proteins and damaged organelles, has been implicated in neurodegenerative diseases, including motor neuron disorders. Motor neuron targeted upregulation of autophagy may serve as a promising therapeutic approach. Lanthionine k...

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Bibliographic Details
Main Authors: Maria A. Gonzalez Porras, Heather M. Gransee, Travis T. Denton, Dunxin Shen, Kevin L. Webb, C. Jeffrey Brinker, Achraf Noureddine, Gary C. Sieck, Carlos B. Mantilla
Format: Article
Language:English
Published: Nature Portfolio 2023-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-29437-8

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https://doi.org/10.1038/s41598-023-29437-8

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