The onset of rare earth metallosis begins with renal gadolinium-rich nanoparticles from magnetic resonance imaging contrast agent exposure

Abstract The leitmotifs of magnetic resonance imaging (MRI) contrast agent-induced complications range from acute kidney injury, symptoms associated with gadolinium exposure (SAGE)/gadolinium deposition disease, potentially fatal gadolinium encephalopathy, and irreversible systemic fibrosis. Gadolin...

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Bibliographic Details
Main Authors: Joshua DeAguero, Tamara Howard, Donna Kusewitt, Adrian Brearley, Abdul-Mehdi Ali, James H. Degnan, Stephen Jett, John Watt, G. Patricia Escobar, Karol Dokladny, Brent Wagner
Format: Article
Language:English
Published: Nature Portfolio 2023-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-28666-1