Recent Progress in Modulation of WD40-Repeat Domain 5 Protein (WDR5): Inhibitors and Degraders

WD40-repeat (WDR) domain proteins play a crucial role in mediating protein–protein interactions that sustain oncogenesis in human cancers. One prominent example is the interaction between the transcription factor MYC and its chromatin co-factor, WD40-repeat domain protein 5 (WDR5), which is essentia...

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Bibliographic Details
Main Authors: Raju Gurung, Darlami Om, Rabin Pun, Soonsil Hyun, Dongyun Shin
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/15/15/3910