Functional performance of a bi-layered chitosan-nano-hydroxyapatite osteochondral scaffold: a pre-clinical in vitro tribological study

Functional performance of a bi-layered chitosan-nano-hydroxyapatite osteochondral scaffold: a pre-clinical in vitro tribological study

Osteochondral grafts are used for repair of focal osteochondral lesions. Autologous grafts are the gold standard treatment; however, limited graft availability and donor site morbidity restrict use. Therefore, there is a clinical need for different graft sources/materials which replicate natural car...

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Bibliographic Details
Main Authors: Raelene M. Cowie, Laura Macri-Pellizzeri, Jane McLaren, William J. Sanderson, Reda M. Felfel, Colin A. Scotchford, Brigitte E. Scammell, David M. Grant, Virginie Sottile, Louise M. Jennings
Format: Article
Language:English
Published: The Royal Society 2024-01-01
Series:Royal Society Open Science
Subjects:
chitosan
tribology
osteochondral graft
natural knee joint
joint simulation
Online Access:https://royalsocietypublishing.org/doi/10.1098/rsos.230431

Internet

https://royalsocietypublishing.org/doi/10.1098/rsos.230431

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