Prediction of protein solubility based on sequence physicochemical patterns and distributed representation information with DeepSoluE
Abstract Background Protein solubility is a precondition for efficient heterologous protein expression at the basis of most industrial applications and for functional interpretation in basic research. However, recurrent formation of inclusion bodies is still an inevitable roadblock in protein scienc...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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BMC
2023-01-01
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| Series: | BMC Biology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12915-023-01510-8 |