Identification of IGF1, SLC4A4, WWOX, and SFMBT1 as hypertension susceptibility genes in Han Chinese with a genome-wide gene-based association study.

Identification of IGF1, SLC4A4, WWOX, and SFMBT1 as hypertension susceptibility genes in Han Chinese with a genome-wide gene-based association study.

Hypertension is a complex disorder with high prevalence rates all over the world. We conducted the first genome-wide gene-based association scan for hypertension in a Han Chinese population. By analyzing genome-wide single-nucleotide-polymorphism data of 400 matched pairs of young-onset hypertensive...

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Bibliographic Details
Main Authors: Hsin-Chou Yang, Yu-Jen Liang, Jaw-Wen Chen, Kuang-Mao Chiang, Chia-Min Chung, Hung-Yun Ho, Chih-Tai Ting, Tsung-Hsien Lin, Sheng-Hsiung Sheu, Wei-Chuan Tsai, Jyh-Hong Chen, Hsin-Bang Leu, Wei-Hsian Yin, Ting-Yu Chiu, Ching-luan Chern, Shing-Jong Lin, Brian Tomlinson, Youling Guo, Pak C Sham, Stacey S Cherny, Tai Hing Lam, G Neil Thomas, Wen-Harn Pan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3315540?pdf=render

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http://europepmc.org/articles/PMC3315540?pdf=render

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