Synthesis, Characterization and In Vitro Evaluation of Novel 5-Ene-thiazolo[3,2-<i>b</i>][1,2,4]triazole-6(5<i>H</i>)-ones as Possible Anticancer Agents

Synthesis, Characterization and In Vitro Evaluation of Novel 5-Ene-thiazolo[3,2-<i>b</i>][1,2,4]triazole-6(5<i>H</i>)-ones as Possible Anticancer Agents

The present paper is devoted to the search for drug-like molecules with anticancer properties using the thiazolo[3,2-<i>b</i>][1,2,4]triazole-6-one scaffold. A series of 24 novel thiazolo-[3,2-<i>b</i>][1,2,4]triazole-6-ones with 5-aryl(heteryl)idene- and 5-aminomethylidene-m...

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Bibliographic Details
Main Authors: Serhii Holota, Sergiy Komykhov, Stepan Sysak, Andrzej Gzella, Andriy Cherkas, Roman Lesyk
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Molecules
Subjects:
thiazolo[3,2-<i>b</i>][1,2,4]triazole-6(5<i>H</i>)-ones
multicomponent reactions
<i>Z</i>/<i>E</i>-isomers
anticancer activity
SAR
Online Access:https://www.mdpi.com/1420-3049/26/4/1162

Internet

https://www.mdpi.com/1420-3049/26/4/1162

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