Whole exome sequencing with a focus on cardiac disease-associated genes in families of sudden unexplained deaths in Yunnan, southwest of China

Whole exome sequencing with a focus on cardiac disease-associated genes in families of sudden unexplained deaths in Yunnan, southwest of China

Abstract Objectives To explore the causes of sudden unexpected death (SUD) and to search for high-risk people, whole exome sequencing (WES) was performed in families with SUDs.  Methods Whole exome sequencing of 25 people from 14 SUD families were screened based on cardiac disease-associated gene va...

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Bibliographic Details
Main Authors: Si-Jie Wei, Jin-Liang Du, Yue-Bing Wang, Peng-Fei Qu, Lin Ma, Zhong-Chun Sun, Xue Tang, Kai Liu, Yan-Mei Xi, Sheng-Jie Nie, Peng-Lin Jia, Wu Long, Yong-Qiang Qu, Yu-Hua Li, Pu-Ping Lei
Format: Article
Language:English
Published: BMC 2023-01-01
Series:BMC Genomics
Subjects:
Sudden unexplained death
Negative autopsy
Whole exome sequencing
Pathogenic variants
Online Access:https://doi.org/10.1186/s12864-022-09097-0

Internet

https://doi.org/10.1186/s12864-022-09097-0

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