Globally defining the effects of mutations in a picornavirus capsid
The capsids of non-enveloped viruses are highly multimeric and multifunctional protein assemblies that play key roles in viral biology and pathogenesis. Despite their importance, a comprehensive understanding of how mutations affect viral fitness across different structural and functional attributes...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2021-01-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/64256 |