Insights into the pharmacodynamics and pharmacokinetics of meldonium after exposure to acute high altitude

Objective: Meldonium, a well-known cardioprotective drug, has been reported to be protective against pulmonary injury at high altitudes; however, the pharmacodynamics of meldonium in other vital organs under acute high-altitude injury are less investigated and the related pharmacokinetics have not b...

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Bibliographic Details
Main Authors: Fengying Liu, Xin Sui, Qian Wang, Jinglai Li, Weijie Yang, Yi Yang, Zhenyu Xiao, Yangyang Sun, Xiaoxuan Guo, Xinyi Yang, Jun Yang, Yongan Wang, Yuan Luo
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1119046/full