Proliferation and migration of ML1 follicular thyroid cancer cells are inhibited by IU1 targeting USP14: role of proteasome and autophagy flux

Proliferation and migration of ML1 follicular thyroid cancer cells are inhibited by IU1 targeting USP14: role of proteasome and autophagy flux

USP14 is a deubiquitinating enzyme involved in protein degradation by interacting with the proteasome and removal of poly-ubiquitin chains on target proteins. USP14 can influence cellular processes such as cell survival, DNA repair, ER stress, endocytosis, and the inflammatory response. USP14 furthe...

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Bibliographic Details
Main Authors: Vignesh Srinivasan, Muhammad Yasir Asghar, Sadia Zafar, Kid Törnquist, Dan Lindholm
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
USP14
proteasome
autophagy
thyroid cancer
cell proliferation
cell migration
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2023.1234204/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2023.1234204/full

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