Oral Administration of P. gingivalis Induces Dysbiosis of Gut Microbiota and Impaired Barrier Function Leading to Dissemination of Enterobacteria to the Liver.

Oral Administration of P. gingivalis Induces Dysbiosis of Gut Microbiota and Impaired Barrier Function Leading to Dissemination of Enterobacteria to the Liver.

Although periodontitis has been implicated as a risk factor for various systemic diseases, the precise mechanisms by which periodontitis induces systemic disease remain to be elucidated. We have previously revealed that repeated oral administration of Porphyromonas gingivalis elicits endotoxemia via...

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Bibliographic Details
Main Authors: Mayuka Nakajima, Kei Arimatsu, Tamotsu Kato, Yumi Matsuda, Takayoshi Minagawa, Naoki Takahashi, Hiroshi Ohno, Kazuhisa Yamazaki
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4517782?pdf=render

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http://europepmc.org/articles/PMC4517782?pdf=render

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