Heart rhythm in vitro: measuring stem cell-derived pacemaker cells on microelectrode arrays

Heart rhythm in vitro: measuring stem cell-derived pacemaker cells on microelectrode arrays

BackgroundCardiac arrhythmias have markedly increased in recent decades, highlighting the urgent need for appropriate test systems to evaluate the efficacy and safety of new pharmaceuticals and the potential side effects of established drugs.MethodsThe Microelectrode Array (MEA) system may be a suit...

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Bibliographic Details
Main Authors: Sophie Kussauer, Patrick Dilk, Moustafa Elleisy, Claudia Michaelis, Sarina Lichtwark, Christian Rimmbach, Robert David, Julia Jung
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
microelectrode array
pacemaker cells
cardiomyocytes
in vitro drug testing
conduction velocity
embryoid bodies
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2024.1200786/full

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https://www.frontiersin.org/articles/10.3389/fcvm.2024.1200786/full

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