MMP‐2 regulates Src activation via repression of the CHK/MATK tumor suppressor in osteosarcoma

Abstract Background Doxorubicin, a first‐line anticancer drug for osteosarcoma treatment, has been the subject of recent research exploring the mechanisms behind its chemoresistance and its ability to enhance cell migration at sublethal concentrations. Matrix metalloproteinase‐2 (MMP‐2), a type IV c...

Full description

Bibliographic Details
Main Authors: Deanna V. Maybee, Christopher R. Cromwell, Basil P. Hubbard, Mohammad A. M. Ali
Format: Article
Language:English
Published: Wiley 2024-02-01
Series:Cancer Reports
Subjects:
Online Access:https://doi.org/10.1002/cnr2.1946