TNIK drives castration-resistant prostate cancer via phosphorylating EGFR

TNIK drives castration-resistant prostate cancer via phosphorylating EGFR

Summary: The development of castration-resistant prostate cancer (CRPC) is driven by intricate genetic and epigenetic mechanisms. Traf2- and Nck-interacting kinase (TNIK) has been reported as a serine/threonine kinase associated with tumor cell proliferation or unfavorable cancer behavior. The micro...

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Bibliographic Details
Main Authors: Jianing Guo, Jiaming Liang, Youzhi Wang, Tao Guo, Yihao Liao, Boqiang Zhong, Shuyue Guo, Qian Cao, Junbo Li, Amilcar Flores-Morales, Yuanjie Niu, Ning Jiang
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:iScience
Subjects:
Biochemistry
Molecular biology
Cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223027906

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http://www.sciencedirect.com/science/article/pii/S2589004223027906

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