The protein arginine methyltransferase PRMT9 attenuates MAVS activation through arginine methylation

The protein arginine methyltransferase PRMT9 attenuates MAVS activation through arginine methylation

Abstract The signaling adaptor MAVS forms prion-like aggregates to activate the innate antiviral immune response after viral infection. However, spontaneous aggregation of MAVS can lead to autoimmune diseases. The molecular mechanism that prevents MAVS from spontaneous aggregation in resting cells h...

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Bibliographic Details
Main Authors: Xuemei Bai, Chao Sui, Feng Liu, Tian Chen, Lei Zhang, Yi Zheng, Bingyu Liu, Chengjiang Gao
Format: Article
Language:English
Published: Nature Portfolio 2022-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-32628-y

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https://doi.org/10.1038/s41467-022-32628-y

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