Intestinal Reg4 deficiency confers susceptibility to high-fat diet-induced liver steatosis by increasing intestinal fat absorption in mice

Intestinal Reg4 deficiency confers susceptibility to high-fat diet-induced liver steatosis by increasing intestinal fat absorption in mice

Background & Aims: Regenerating gene family member 4 (REG4) is a novel marker for enteroendocrine cells and is selectively expressed in specialised enteroendocrine cells of the small intestine. However, the exact roles of REG4 are largely unknown. In this study we investigate the effects of...

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Bibliographic Details
Main Authors: Ying Wang, Weihui Yan, Ying Lu, Jun Du, Xinbei Tian, Bo Wu, Shicheng Peng, Beilin Gu, Wei Cai, Yongtao Xiao
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:JHEP Reports
Subjects:
Liver steatosis
Fat absorption
Reg4
AMPK
Childhood obesity
Online Access:http://www.sciencedirect.com/science/article/pii/S2589555923000319

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http://www.sciencedirect.com/science/article/pii/S2589555923000319

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