Accumulation of Senescent Neural Cells in Murine Lupus With Depression-Like Behavior

Accumulation of Senescent Neural Cells in Murine Lupus With Depression-Like Behavior

Neuropsychiatric manifestations targeting the central, peripheral, and autonomic nervous system are common in systemic lupus erythematosus (SLE); collectively, these symptoms are termed neuropsychiatric SLE (NPSLE). Among a wide variety of neuropsychiatric symptoms, depression is observed in about 2...

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Bibliographic Details
Main Authors: Yuki Saito, Maki Miyajima, Sena Yamamoto, Tsukasa Sato, Norihiro Miura, Mineko Fujimiya, Takako S. Chikenji
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Immunology
Subjects:
systemic lupus erythematosus
senescence
depression
inflammation
SASP (senescence-associated secretory phenotype)
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.692321/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.692321/full

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