Crosstalk and signalling switches in mitogen-activated protein kinase cascades

Mitogen-activated protein kinase (MAPK) cascades control cell fate decisions, such as proliferation, differentiation and apoptosis by integrating and processing intra- and extracellular cues. However, similar MAPK kinetic profiles can be associated with opposing cellular decisions depending on cell...

Full description

Bibliographic Details
Main Authors: Dirk eFey, David R Croucher, Walter eKolch, Boris N Kholodenko
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-09-01
Series:Frontiers in Physiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2012.00355/full