Deep-prior ODEs augment fluorescence imaging with chemical sensors

Abstract To study biological signalling, great effort goes into designing sensors whose fluorescence follows the concentration of chemical messengers as closely as possible. However, the binding kinetics of the sensors are often overlooked when interpreting cell signals from the resulting fluorescen...

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Bibliographic Details
Main Authors: Thanh-an Pham, Aleix Boquet-Pujadas, Sandip Mondal, Michael Unser, George Barbastathis
Format: Article
Language:English
Published: Nature Portfolio 2024-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-53232-2