Oral delivery of Hyperimmune bovine serum antibodies against CS6-expressing enterotoxigenic Escherichia coli as a prophylactic against diarrhea

Oral delivery of Hyperimmune bovine serum antibodies against CS6-expressing enterotoxigenic Escherichia coli as a prophylactic against diarrhea

Background . Oral administration of bovine antibodies active against enterotoxigenic Escherichia coli (ETEC) have demonstrated safety and efficacy against diarrhea in human challenge trials. The efficacy of bovine serum immunoglobulins (BSIgG) against recombinant colonization factor CS6 or whole cel...

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Bibliographic Details
Main Authors: KR Talaat, CK Porter, AL Bourgeois, TK Lee, CA Duplessis, M Maciel, RL Gutierrez, B DeNearing, B Adjoodani, R Adkinson, KJ Testa, B Feijoo, AN Alcala, J Brubaker, A Beselman, S Chakraborty, D Sack, J Halpern, S Trop, H Wu, J Jiao, E Sullivan, MS Riddle, SS Joseph, ST Poole, MG Prouty
Format: Article
Language:English
Published: Taylor & Francis Group 2020-11-01
Series:Gut Microbes
Subjects:
enterotoxigenic escherichia coli
controlled human infection model
diarrhea
passive prophylaxis
Online Access:http://dx.doi.org/10.1080/19490976.2020.1732852

Internet

http://dx.doi.org/10.1080/19490976.2020.1732852

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