Plasmacytoid Dendritic Cell, Slan<sup>+</sup>-Monocyte and Natural Killer Cell Counts Function as Blood Cell-Based Biomarkers for Predicting Responses to Immune Checkpoint Inhibitor Monotherapy in Non-Small Cell Lung Cancer Patients

Plasmacytoid Dendritic Cell, Slan<sup>+</sup>-Monocyte and Natural Killer Cell Counts Function as Blood Cell-Based Biomarkers for Predicting Responses to Immune Checkpoint Inhibitor Monotherapy in Non-Small Cell Lung Cancer Patients

The advent of immune checkpoint inhibitors (ICIs), for instance, programmed cell death 1 (PD-1)/PD-1 ligand 1 (PD-L1) blockers, has greatly improved the outcome of patients affected by non-small cell lung cancer (NSCLC). However, most NSCLC patients either do not respond to ICI monotherapy or develo...

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Bibliographic Details
Main Authors: Francesca Pettinella, Chiara Lattanzi, Marta Donini, Elena Caveggion, Olivia Marini, Giulia Iannoto, Sara Costa, Elena Zenaro, Tiago Moderno Fortunato, Sara Gasperini, Matteo Giani, Lorenzo Belluomini, Marco Sposito, Jessica Insolda, Ilaria Mariangela Scaglione, Michele Milella, Annalisa Adamo, Ornella Poffe, Vincenzo Bronte, Stefano Dusi, Marco A. Cassatella, Stefano Ugel, Sara Pilotto, Patrizia Scapini
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Cancers
Subjects:
immune checkpoint inhibitors
PD-1/PD-L1
innate immune cells
blood biomarkers
non-small cell lung cancer
Online Access:https://www.mdpi.com/2072-6694/15/21/5285

Internet

https://www.mdpi.com/2072-6694/15/21/5285

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