Mechanisms of Activation of Receptor Tyrosine Kinases: Monomers or Dimers
Receptor tyrosine kinases (RTKs) play essential roles in cellular processes, including metabolism, cell-cycle control, survival, proliferation, motility and differentiation. RTKs are all synthesized as single-pass transmembrane proteins and bind polypeptide ligands, mainly growth factors. It has lon...
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| Format: | Article |
| Language: | English |
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MDPI AG
2014-04-01
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| Series: | Cells |
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| Online Access: | http://www.mdpi.com/2073-4409/3/2/304 |