A straightforward microfluidic-based approach toward optimizing transduction efficiency of HIV-1-derived lentiviral vectors in BCP-ALL cells

Background: HIV-1-derived lentiviral vectors (LVs) are capable of transducing human cells by integrating the transgene into the host genome. In order to do that, LVs should have enough time and space to interact with the surface of the target cells. Herein, we used a microfluidic system to facilitat...

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Bibliographic Details
Main Authors: Seyed Esmaeil Ahmadi, Rima Manafi Shabestari, Amir Asri kojabad, Majid Safa
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Biotechnology Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2215017X23000127