Alcohol exposure decreases CREB binding protein expression and histone acetylation in the developing cerebellum.

Alcohol exposure decreases CREB binding protein expression and histone acetylation in the developing cerebellum.

Fetal alcohol exposure affects 1 in 100 children making it the leading cause of mental retardation in the US. It has long been known that alcohol affects cerebellum development and function. However, the underlying molecular mechanism is unclear.We demonstrate that CREB binding protein (CBP) is wide...

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Bibliographic Details
Main Authors: Weixiang Guo, Erin L Crossey, Li Zhang, Stefano Zucca, Olivia L George, C Fernando Valenzuela, Xinyu Zhao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3104983?pdf=render

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http://europepmc.org/articles/PMC3104983?pdf=render

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