A random walk approach to estimate the confinement of α-particle emitters in nanoparticles for targeted radionuclide therapy

A random walk approach to estimate the confinement of α-particle emitters in nanoparticles for targeted radionuclide therapy

Abstract Background Targeted radionuclide therapy is a highly efficient but still underused treatment modality for various types of cancers that uses so far mainly readily available β-emitting radionuclides. By using α-particle emitters several shortcomings due to hypoxia, cell proliferation and in...

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Bibliographic Details
Main Authors: Uwe Holzwarth, Isaac Ojea Jimenez, Luigi Calzolai
Format: Article
Language:English
Published: SpringerOpen 2018-05-01
Series:EJNMMI Radiopharmacy and Chemistry
Subjects:
Targeted radionuclide therapy
α-particle emitters
225Ac
224Ra
223Ra
Recoil energy
Online Access:http://link.springer.com/article/10.1186/s41181-018-0042-3

Internet

http://link.springer.com/article/10.1186/s41181-018-0042-3

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