Brazilin from Caesalpinia sappan inhibits viral infection against PRRSV via CD163ΔSRCR5 MARC-145 cells: an in silico and in vitro studies

Brazilin from Caesalpinia sappan inhibits viral infection against PRRSV via CD163ΔSRCR5 MARC-145 cells: an in silico and in vitro studies

Abstract This research aimed to identify bioactive compounds from Caesalpinia sappan extract that function as novel porcine reproductive and respiratory syndrome virus (PRRSV) infection inhibitors by computational molecular screening. We obtained a set of small-molecule compounds predicted to target...

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Bibliographic Details
Main Authors: Chaiwat Arjin, Suriya Tateing, Nuttha Potapohn, Jirapat Arunorat, Kidsadagon Pringproa, Chompunut Lumsangkul, Mintra Seel-audom, Warintorn Ruksiriwanich, Korawan Sringarm
Format: Article
Language:English
Published: Nature Portfolio 2022-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-26206-x

Internet

https://doi.org/10.1038/s41598-022-26206-x

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